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Expected timeline: Days 1-3: Continued acute symptoms, peptide beginning to accumulate Days 4-7: Inflammation reduction often noticeable, pain decreasing Week 2-3: Significant improvement in most acute strains Week 4-6: Return to normal function, consider tapering Complementary approaches: Gentle movement, avoiding complete rest

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Another study by this group [167] reported that administration of multiple doses of the acetylcholine receptor agonist carbacol decreased microglial activation and inflammation, and decreased brain damage after hypoxia-ischemia in 7 day old rat pups