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133 , 134 In addition, BPC 157 recovers also smooth muscle functions, that is, sphincters 144 - 147 (lower esophageal, pyloric, 144 - 146 urinary, 147 pupil 112 ), upon direct injury (stretching), 144 - 147 indirect injury (fistula, 82 - 84 anastomosis, 87 ) or damaging agents (alcohol, 52 potassium or magnesium over-load, 43 , 111 NSAIDs, 115 neuroleptics, 116 NO-agents, 112 , 116 atropine 112 ) application
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Deng et al., 2013) have several limitations (i.e., local application, carrier addition, and weak and uncertain peptide activity of its own (Seiwerth et al., 2018)), delaying practical realization of the growth factor healing concept