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Colchicine para-aminosalicylic acid and heavy alcohol intake for longer than 2 weeks may produce malabsorption of vitamin B 12

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Furthermore, organic anion transporter (OAT)1 has been demonstrated to be involved in the transport of UA in a dose- and time-dependent manner, and it has been suggested to serve a role in the first step of urate secretion, specifically, the uptake of urate from the peritubular space into renal tubular cells (40,41)