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These early changes are not universal

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20,21 Although postnatal NAC supplementation in preterm infants failed to confer any significant benefit on mortality and morbidity, 22 several studies suggest NAC administration per partum to pregnant women with chorioamnionitis cases improved neonatal outcomes, as attested by a reduction in the need for intensive resuscitation, and in the risk of intraventricular hemorrhage (IVH) and BPD, compared to placebo