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[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Doshi S.B., Khullar K., Sharma R.K., Agarwal A

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Despite the fact that familial AD (FAD) contribution to the overall burden of AD cases could be considered negligible, its discovery has boosted the generation of a diverse transgenic mouse models carrying a combination of human mutations that triggers pathogenic events sharing commonalities with human sporadic AD, such as Aβ deposition and progressive cognitive decline