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When the intestines are dehydrated, there isn’t enough water to add to the stools, resulting in dry, hard lumps (referred to as type 1 stools in the Bristol Stool Chart)

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Similarly, to compare the relative effects of multiple NNMT inhibitors on NNMT activity in cultured adipocytes, differentiated adipocytes in 6-well plates were treated with 10 µM test compound for 24 h

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