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In particular, they demonstrate reduced NF-κB interaction and decreased transrepression of proinflammatory and apoptotic genes compared to other isoforms ( in vivo studies of GR mRNA/protein isoform overexpression are required to confirm GR isoform-specific functions

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Further studies have shown that BPC-157 has been able to promote the healing of tendons and ligaments by cell migration, tendon outgrowth and cell survival in rodents that had a rupture in their Achilles tendon