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(Life Sci, 2000) reported upregulated matrix metalloproteinase-2 alongside its tissue inhibitors in fibroblast culture, and Maquart et al

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Its documented activity in preclinical research spans gastroprotection against multiple forms of mucosal damage, accelerated tendon, ligament, and muscle healing, promotion of angiogenesis and blood vessel repair, anti-inflammatory activity at the tissue level, and modulation of growth factors involved in tissue remodeling