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Combination therapy has shown somewhat higher rates of GI events compared to either monotherapy, and slow, gradual dose titration significantly improves tolerability
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Skin benefits : Reduces fine lines and wrinkles Improves skin thickness Enhances firmness and elasticity Evens skin tone Reduces hyperpigmentation Promotes healing of scars and damage Improves texture Mechanisms : Stimulates collagen I and III production Promotes elastin synthesis Enhances hyaluronic acid Improves blood flow to skin Antioxidant protection Protocol : Topical : Apply serum/cream 2x daily Injectable : 1-2mg daily subcutaneous Expected results : Visible improvement in 8-12 weeks, significant changes by 6 months
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